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While the exact cause of lupus is still unknown, researchers believe that a combination of genetic, environmental, and hormonal factors play a role in its development

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Kluck R, Muller S, Jagodzinski C, Hohenfellner K, Buscher A, Kemper MJ, Oh J, Billing H, Thumfart J, Weber LT, Acham-Roschitz B, Arbeiter K, Tonshoff B, Hagenberg M, Kanzelmeyer N, Pavicic L, Haffner D, Zivicnjak M (2022) Body growth, upper arm fat area, and clinical parameters in children with nephropathic cystinosis compared with other pediatric chronic kidney disease entities

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Furthermore, chronic treatment with the GLP-1 mimetic liraglutide induces similar improvements on glucose tolerance despite the loss of PNS or CNS-GLP-1R expression, indicating that non-neuronal GLP-1R signaling is sufficient for the long-term improvements in glucose homeostasis induced by liraglutide in mice (Sisley et al., 2014)

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[The tocolytic activity of melatonin]

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